Source code for antspynet.utilities.randomly_transform_image_data

import ants

import numpy as np

[docs]def randomly_transform_image_data(reference_image, input_image_list, segmentation_image_list=None, number_of_simulations=10, transform_type='affine', sd_affine=0.02, deformation_transform_type="bspline", number_of_random_points=1000, sd_noise=10.0, number_of_fitting_levels=4, mesh_size=1, sd_smoothing=4.0, input_image_interpolator='linear', segmentation_image_interpolator='nearestNeighbor'): """ Randomly transform image data (optional: with corresponding segmentations). Apply rigid, affine and/or deformable maps to an input set of training images. The reference image domain defines the space in which this happens. Arguments --------- reference_image : ANTsImage Defines the spatial domain for all output images. If the input images do not match the spatial domain of the reference image, we internally resample the target to the reference image. This could have unexpected consequences. Resampling to the reference domain is performed by testing using ants.image_physical_space_consistency then calling ants.resample_image_to_target with failure. input_image_list : list of lists of ANTsImages List of lists of input images to warp. The internal list sets contain one or more images (per subject) which are assumed to be mutually aligned. The outer list contains multiple subject lists which are randomly sampled to produce output image list. segmentation_image_list : list of ANTsImages List of segmentation images corresponding to the input image list (optional). number_of_simulations : integer Number of simulated output image sets. transform_type : string One of the following options: "translation", "rigid", "scaleShear", "affine", "deformation", "affineAndDeformation". sd_affine : float Parameter dictating deviation amount from identity for random linear transformations. deformation_transform_type : string "bspline" or "exponential". number_of_random_points : integer Number of displacement points for the deformation field. sd_noise : float Standard deviation of the displacement field. number_of_fitting_levels : integer Number of fitting levels (bspline deformation only). mesh_size : int or n-D tuple Determines fitting resolution (bspline deformation only). sd_smoothing : float Standard deviation of the Gaussian smoothing in mm (exponential field only). input_image_interpolator : string One of the following options: "nearestNeighbor", "linear", "gaussian", "bSpline". segmentation_image_interpolator : string Only "nearestNeighbor" is currently available. Returns ------- list of lists of transformed images Example ------- >>> import ants >>> image1_list = list() >>> image1_list.append(ants.image_read(ants.get_ants_data("r16"))) >>> image2_list = list() >>> image2_list.append(ants.image_read(ants.get_ants_data("r64"))) >>> input_segmentations = list() >>> input_segmentations.append(ants.threshold_image(image1, "Otsu", 3)) >>> input_segmentations.append(ants.threshold_image(image2, "Otsu", 3)) >>> input_images = list() >>> input_images.append(image1_list) >>> input_images.append(image2_list) >>> data = antspynet.randomly_transform_image_data(image1, >>> input_images, input_segmentations, sd_affine=0.02, >>> transform_type = "affineAndDeformation" ) """ def polar_decomposition(X): U, d, V = np.linalg.svd(X, full_matrices=False) P = np.matmul(U, np.matmul(np.diag(d), np.transpose(U))) Z = np.matmul(U, V) if np.linalg.det(Z) < 0: n = X.shape[0] reflection_matrix = np.identity(n) reflection_matrix[0,0] = -1.0 Z = np.matmul(Z, reflection_matrix) return({"P" : P, "Z" : Z, "Xtilde" : np.matmul(P, Z)}) def create_random_linear_transform(image, fixed_parameters, transform_type='affine', sd_affine=0.02): transform = ants.create_ants_transform(transform_type= "AffineTransform", precision='float', dimension=image.dimension) ants.set_ants_transform_fixed_parameters(transform, fixed_parameters) identity_parameters = ants.get_ants_transform_parameters(transform) random_epsilon = np.random.normal(loc=0, scale=sd_affine, size=len(identity_parameters)) if transform_type == 'translation': random_epsilon[:(len(identity_parameters) - image.dimension)] = 0 random_parameters = identity_parameters + random_epsilon random_matrix = np.reshape( random_parameters[:(len(identity_parameters) - image.dimension)], newshape=(image.dimension, image.dimension)) decomposition = polar_decomposition(random_matrix) if transform_type == "rigid": random_matrix = decomposition['Z'] elif transform_type == "affine": random_matrix = decomposition['Xtilde'] elif transform_type == "scaleShear": random_matrix = decomposition['P'] random_parameters[:(len(identity_parameters) - image.dimension)] = \ np.reshape(random_matrix, newshape=(len(identity_parameters) - image.dimension)) ants.set_ants_transform_parameters(transform, random_parameters) return(transform) def create_random_displacement_field_transform(image, field_type="bspline", number_of_random_points=1000, sd_noise=10.0, number_of_fitting_levels=4, mesh_size=1, sd_smoothing=4.0): displacement_field = ants.simulate_displacement_field(image, field_type=field_type, number_of_random_points=number_of_random_points, sd_noise=sd_noise, enforce_stationary_boundary=True, number_of_fitting_levels=number_of_fitting_levels, mesh_size=mesh_size, sd_smoothing=sd_smoothing) return(ants.transform_from_displacement_field(displacement_field)) admissible_transforms = ("translation", "rigid", "scaleShear", "affine", "affineAndDeformation", "deformation") if not transform_type in admissible_transforms: raise ValueError("The specified transform is not a possible option. Please see help menu.") # Get the fixed parameters from the reference image. fixed_parameters = ants.get_center_of_mass(reference_image) number_of_subjects = len(input_image_list) random_indices = np.random.choice(number_of_subjects, size=number_of_simulations, replace=True) simulated_image_list = list() simulated_segmentation_image_list = list() simulated_transforms = list() for i in range(number_of_simulations): single_subject_image_list = input_image_list[random_indices[i]] single_subject_segmentation_image = None if segmentation_image_list is not None: single_subject_segmentation_image = segmentation_image_list[random_indices[i]] if ants.image_physical_space_consistency(reference_image, single_subject_image_list[0]) is False: for j in range(len(single_subject_image_list)): single_subject_image_list.append( ants.resample_image_to_target(single_subject_image_list[j], reference_image, interp_type=input_image_interpolator)) if single_subject_segmentation_image is not None: single_subject_segmentation_image = \ ants.resample_image_to_target(single_subject_segmentation_image, reference_image, interp_type=segmentation_image_interpolator) transforms = list() if transform_type == 'deformation': deformable_transform = create_random_displacement_field_transform( reference_image, deformation_transform_type, number_of_random_points, sd_noise, number_of_fitting_levels, mesh_size, sd_smoothing) transforms.append(deformable_transform) elif transform_type == 'affineAndDeformation': deformable_transform = create_random_displacement_field_transform( reference_image, deformation_transform_type, number_of_random_points, sd_noise, number_of_fitting_levels, mesh_size, sd_smoothing) linear_transform = create_random_linear_transform(reference_image, fixed_parameters, 'affine', sd_affine) transforms.append(deformable_transform) transforms.append(linear_transform) else: linear_transform = create_random_linear_transform(reference_image, fixed_parameters, transform_type, sd_affine) transforms.append(linear_transform) simulated_transforms.append(ants.compose_ants_transforms(transforms)) single_subject_simulated_image_list = list() for j in range(len(single_subject_image_list)): single_subject_image = single_subject_image_list[j] single_subject_simulated_image_list.append(ants.apply_ants_transform_to_image( simulated_transforms[i], single_subject_image, reference=reference_image, interpolation=input_image_interpolator.lower())) simulated_image_list.append(single_subject_simulated_image_list) if single_subject_segmentation_image is not None: simulated_segmentation_image_list.append(ants.apply_ants_transform_to_image( simulated_transforms[i], single_subject_segmentation_image, reference=reference_image, interpolation=segmentation_image_interpolator.lower())) if segmentation_image_list is None: return({'simulated_images' : simulated_image_list, 'simulated_transforms' : simulated_transforms, 'which_subject' : random_indices}) else: return({'simulated_images' : simulated_image_list, 'simulated_segmentation_images' : simulated_segmentation_image_list, 'simulated_transforms' : simulated_transforms, 'which_subject' : random_indices})